英語版投稿 - 健康長寿代謝制御研究センター │ 熊本大学大学院生命科学研究部附属

The work by Assis. Prof. Yuichiro ARIMA and Prof. Kenichi TSUJITA is published in Journal of the American College of Cardiology.

2019-01-15

Myocardial Ischemia Suppresses Ketone Body Utilization

Yuichiro Arima, Yasuhiro Izumiya, Toshifumi Ishida, Seiji Takashio, Masanobu Ishii, Daisuke Sueta, Koichiro Fujisue, Kenji Sakamoto, Koichi Kaikita, Kenichi Tsujita

DOI:　doi.org/10.1016/j.jacc.2018.10.040

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The collaborative work by Dana-Farber Cancer Institute and Prof. Hideo BABA is published in Clinical Cancer Research.

2018-12-01

Amplification of Wild-type KRAS Imparts Resistance to Crizotinib in MET Exon 14 Mutant Non-Small Cell Lung Cancer.

Bahcall M, Awad MM, Sholl LM, Wilson FH, Xu M, Wang S, Palakurthi S, Choi J, Ivanova EV, Leonardi GC, Ulrich BC, Paweletz CP, Kirschmeier PT, Watanabe M, Baba H, Nishino M, Nagy RJ, Lanman RB, Capelletti M, Chambers ES, Redig AJ, VanderLaan PA, Costa DB, Imamura Y, Janne PA

Clin Cancer Res 24(23):5963-5976, 2018.

DOI: 10.1158/1078-0432.CCR-18-0876.

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The collaborative work by Azabu Univ. , Keio Univ. and Assoc. Prof. Kyoko MIURA is published in PNAS.

2018-08-27

Responses to pup vocalizations in subordinate naked mole-rats are induced by estradiol ingested through coprophagy of queen’s feces.

Watarai A, Arai N, Miyawaki S, Okano H, Miura K, Mogi K, Kikusui T.

DOI: 10.1073/pnas.1720530115

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The collaborative work by Univ. of California and Assoc. Prof. Toshiro MOROISHI is published in Nature.

2018-08-22

RAP2 mediates mechanoresponses of Hippo pathway

Meng Z., Qiu Y., Lin K.C., Kumar A., Placone J.K., Fang C., Wang K.C., Lu S., Pan M., Hong A.W., Moroishi T., Luo M., Plouffe S.W., Diao Y., Ye Z., Park H.W., Wang X., Yu F.X., Chien S., Wang C.Y., Ren B., Engler A.J., Guan K.L.

DOI：10.1038/s41586-018-0444-0

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The review article by Prof. Kazuya IWAMOTO is published in Molecular Psychiatry.

2018-08-07

Somatic mutations in the human brain: implications for psychiatric research

Masaki Nishioka, Miki Bundo, Kazuya Iwamoto*,Tadafumi Kato*
(*correspondence authors)

DOI:　10.1038/s41380-018-0129-y

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The collaborative work by Dana-Farber Cancer Institute and Prof. Hideo BABA is published in Nature Medicine.

2018-07-23

Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses.

Canadas I, Thummalapalli R, Kim JW, Kitajima S, Jenkins RW, Christensen CL, Campisi M, Kuang Y, Zhang Y, Gjini E, Zhang G, Tian T, Sen DR, Miao D, Imamura Y, Thai T, Piel B, Terai H, Aref AR, Hagan T, Koyama S, Watanabe M, Baba H, Adeni AE, Lydon CA, Tamayo P, Wei Z, Herlyn M, Barbie TU, Uppaluri R, Sholl LM, Sicinska E, Sands J, Rodig S, Wong KK, Paweletz CP, Watanabe H, Barbie DA

Nat Med 24(8):1143-1150, 2018.

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The work by Prof. Kazuya YAMAGATA is published in Nature Communications.

2018-07-19

SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.

Fukuda M, Yoshizawa T, Karim Md. F, Sobuz S. U., Korogi W, Kobayasi D, Okanishi H, Masayoshi T, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K.

掲載誌：Nature Communications 9, 2833 (2018)

DOI: 10.1038/s41467-018-05187-4

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The collaborative work by Univ. of California and Assoc. Prof. Toshiro MOROISHI is published in Nature Communications.

2018-07-09

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.
Martin, D., Degese, M.S., Vitale-Cross, L., Iglesias-Bartolome, R., Valera, J.L.C., Wang, Z., Feng, X., Yeerna, H., Vadmal, V., Moroishi, T., Thorne, R.F., Zaida, M., Siegele, B., Cheong, S.C., Molinolo, A.A., Samuels, Y., Tamayo, P., Guan, K.L., Lippman, S.M., Lyons, J.G., and Gutkind, J.S.
DOI：10.1038/s41467-018-04590-1

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The collaborative work by Dana-Farber Cancer Institute and Prof. Hideo BABA is published in Nature Medicine.

2018-05-28

Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.

Wong GS, Zhou J, Liu JB, Wu Z, Xu X, Li T, Xu D, Schumacher SE, Puschhof J, McFarland J, Zou C, Dulak A, Henderson L, Xu P, O’Day E, Rendak R, Liao WL, Cecchi F, Hembrough T, Schwartz S, Szeto C, Rustgi AK, Wong KK, Diehl JA, Jensen K, Graziano F, Ruzzo A, Fereshetian S, Mertins P, Carr SA, Beroukhim R, Nakamura K, Oki E, Watanabe M, Baba H, Imamura Y, Catenacci D, Bass AJ

Nat Med 24(7):968-977, 2018.

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The collaborative work by Kyushu Univ. and Prof. Yuichi OIKE is published in Cell Reports.

2018-05-15

The autism-related protein CHD8 cooperates with C/EBPβ to regulate adipogenesis.

Kita Y, Katayama Y, Shiraishi T, Oka T, Sato T, Suyama M, Ohkawa Y, Miyata K, Oike Y, Shirane M, Nishiyama M, Nakayama KI.

Cell Rep. 23: 1988-2000, 2018.

doi: 10.1016/j.celrep.2018.04.050.

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